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HHS - 113 - National Toxicology Program Board of Scientific Counselors - Authorized by Law


Committee NameNational Toxicology Program Board of Scientific CounselorsAgency NameDepartment of Health and Human Services
Fiscal Year2022Committee Number113
Original Establishment Date11/15/1978Committee StatusChartered
Actual Termination Date Committee URL
New Committee This FYNoPresidential Appointments*No
Terminated This FYNoMax Number of Members*20
Current Charter Date11/14/2022Designated Fed Officer Position Title*Acting Deputy Director for Policy and Communication, Division of NTP
Date Of Renewal Charter11/14/2024Designated Federal Officer Prefix
Projected Termination Date Designated Federal Officer First Name*Mary
Exempt From Renewal*NoDesignated Federal Officer Middle NameS
Specific Termination AuthorityDesignated Federal Officer Last Name*Wolfe
Establishment Authority*Authorized by LawDesignated Federal Officer SuffixPh.D.
Specific Establishment Authority*42 U.S.C. 217aDesignated Federal Officer Phone*(984) 287-3209
Effective Date Of Authority*11/17/1962Designated Federal Officer Fax*919-541-0295
Exempt From EO 13875 Discretionary CmteNot ApplicableDesignated Federal Officer Email*
Committee Type*Continuing
Committee Function*Other Committee


Agency Recommendation*Continue
Legislation to Terminate RequiredNot Applicable
Legislation StatusNot Applicable
How does cmte accomplish its purpose?*The National Toxicology Program (NTP) Board of Scientific Counselors (BSC) is a technical advisory body established to advise the NTP Executive Committee and NTP Director on matters relating to scientific program content and to evaluate the scientific merits of the intramural and collaborative programs of the NTP. Meetings are open to the public and webcast, written comments are received, and time provided at meetings for oral public comment. Information about BSC meetings can be found at
How is membership balanced?*Members of the BSC are selected from recognized authorities knowledgeable in fields such as toxicology, pharmacology, pathology, biochemistry, epidemiology, mutagenesis, immunology, carcinogenesis, industrial hygiene, reproductive toxicology, and biostatistics. The Secretary, Health and Human Services, appoints members to the BSC. The members review the NTP activities in the above areas and provide scientific oversight to the program.
How frequent & relevant are cmte mtgs?*The BSC typically meets twice annually and convenes working groups and subcommittees to address special programmatic issues as needed. Continuation of the BSC is necessary because there is no other available source that can provide a proper blend of programmatic review and advice needed by the NTP. The BSC met twice in FY2022, on December 8, 2021 and April 19, 2022.
Why advice can't be obtained elsewhere?*Due to the unique function and objectives of the NTP within the public sector, an independent advisory board is required that includes a breadth of scientific expertise within the membership and a membership that can evaluate and advise on activities ranging from basic research to large-scale chemical testing.
Why close or partially close meetings?N/A
Recommendation RemarksCommittee Function - Other, Scientific and Technical Peer Review.

Based on the assignment of duties within the National Toxicology Program, the designated federal officer (DFO) and committee decision maker positions are held by the same individual.

Reports: This committee did not produce any reports during this fiscal year.

Members: David Berube, Weihsueh Chiu, David Eaton, Susan Felter, David Michaels, Anne Ryan, and Susan Tilton were administratively extended as per the Charter, while the 2021 nomination slate is pending.


Outcome Improvement To Health Or Safety*YesAction Reorganize Priorities*No
Outcome Trust In GovernmentYesAction Reallocate ResourcesNo
Outcome Major Policy ChangesNoAction Issued New RegulationsNo
Outcome Advance In Scientific ResearchYesAction Proposed LegislationNo
Outcome Effective Grant MakingNoAction Approved Grants Or Other PaymentsNo
Outcome Improved Service DeliveryYesAction OtherYes
Outcome Increased Customer SatisfactionYesAction CommentThe Committee makes recommendations to federal staff. The National Toxicology Program (NTP) Board of Scientific Counselors (BSC) advises the NTP Executive Committee and NTP Director on matters relating to scientific program content and to evaluate the scientific merits of the intramural and collaborative programs of the NTP.
Outcome Implement Laws/Reg RequirementsNoGrants Review*No
Outcome OtherNoNumber Of Grants Reviewed0
Outcome CommentNANumber Of Grants Recommended0
Cost Savings*NoneDollar Value Of Grants Recommended$0.00
Cost Savings CommentNIH supported basic and clinical research accomplishments often take many years to unfold into new diagnostic tests and new ways to treat and prevent diseases.Grants Review CommentAlthough grant reviews are included in the duties of this Board, there were no grant reviews performed during this fiscal year.
Number Of Recommendations*263Access Contact Designated Fed. Officer*Yes
Number Of Recommendations CommentThe BSC held two meetings and started the process of establishing one Working Group in FY22:

1. The NTP BSC met on December 8, 2021. Agenda topics included presentations and discussion on: (1) State of the DNTP; (2) DNTP Strategic Portfolio; and (3) Looking Forward to 2022 and Beyond.

When asked to share ideas on performance metrics that could be used to assess the State of the DNTP, the BSC provided numerous insightful comments and six recommendations regarding metrics and programmatic evaluation, and use of DNTP-developed methods.

On the topic of the DNTP Strategic Portfolio, the BSC was asked to elaborate on three questions intended to focus on DNTP impact and relevance to emerging public health issues.

a) How should DNTP refine toxicology study and assessment approaches to better understand and account for social determinants of health? The board provided five recommendations regarding interactions between social determinants and toxic exposures, place-based vulnerabilities, and how underlying conditions and stressors may influence response to toxic exposures.

b) How should DNTP selectively adapt current projects to address the disproportionate impacts of climate change on individuals and populations? The board provided six recommendations regarding interactions between different exposures in the context of climate change, heat stress, mycotoxins, immunotoxicity, and disease outcomes in vulnerable populations.

c) How should DNTP define creative approaches to effectively engage stakeholders to increase the impact of DNTP research products? The board provided numerous insightful comments and six recommendations regarding stakeholders’ engagement and training, impact of DNTP reports to the scientific community, and methods for establishing scientific partnerships.

When asked to share ideas and considerations on Looking forward to 2022 and beyond, the BSC provided two comments regarding opportunities for engagement with the scientific community to better identify biomarkers of bioactivity, and to leverage DNTP’s leadership position on how to address the complex problem that mixtures pose for environmental toxicology.

2. The NTP BSC met on April 19, 2022. The meeting held presentations and discussion on the contract concept of Bioinformatics Support for the NIEHS.

The objective of this contract is to provide bioinformatic support to the NIEHS’ Division of the National Toxicology Program (DNTP) and the Division of Intramural Research (DIR) for their diverse research initiatives that involve large, complex, and multidimensional datasets. These groups have need for analyses of data from interrelated disciplines of toxicology, genomics, structural chemistry, high-throughput screening, data and text mining, and high-content-image analysis, and from files downloaded from large, public data repositories. The scope of the required activities and the space and personnel needed to conduct these studies, exceed the resources available at the NIEHS; therefore, there was a request for support through contract mechanisms. The BSC agreed that a contract mechanism is appropriate to support the proposed activities and voted unanimously in favor of the motion to approve the contract concept.

3. The NTP BSC is establishing a Working Group that will be tasked to peer review DNTP’s responses to the collective input on several draft documents. Plans are underway to identify the working group’s membership with potential areas of expertise including environmental epidemiology, environmental neurotoxicology, children’s neurodevelopment, systematic review, meta-analysis, and statistical methodology. This working group will be chaired by the BSC chair, David Eaton, PhD, and includes a second BSC member, David Michaels, PhD. We expect that the working group will be fully populated and its work underway by the end of FY2022. Completion of the working group’s task and presentation of its report to the NTP BSC for their review and action is anticipated in FY 2023.
Access Agency WebsiteNo
% of Recs Fully Implemented*0.00%Access Committee WebsiteYes
% of Recs Fully Implemented CommentDue to the large breadth and complexity of the recommendations made by this committee, staff is unable to determine which recommendations have been fully or partially implemented solely in response to this committee's activities.Access GSA FACA WebsiteYes
% of Recs Partially Implemented*0.00%Access PublicationsNo
% of Recs Partially Implemented CommentNAAccess OtherYes
Agency Feedback*YesAccess CommentContact the Designated Federal Officer.
Agency Feedback Comment*Information is provided to the public at each meeting. The public can view information related to the Committee through the committee’s official website.Narrative Description*The National Toxicology Program Board of Scientific Counselors (Board) is a technical advisory body established to advise the National Toxicology Program (NTP) Executive Committee and Program Director on matters relating to the scientific program content and to evaluate the scientific merits of the intramural and collaborative programs of the NTP, and as requested by the Secretary, undertake peer review of extramural funding applications as required by section 492 of the Public Health Service Act, as amended.
Hide Section - COSTS


Payments to Non-Federal Members*$4,400.00Est Payments to Non-Fed Members Next FY*$4,400.00
Payments to Federal Members*$0.00Est. Payments to Fed Members Next FY*$0.00
Payments to Federal Staff*$70,120.00Estimated Payments to Federal Staff*$61,741.00
Payments to Consultants*$0.00Est. Payments to Consultants Next FY*$0.00
Travel Reimb. For Non-Federal Members*$0.00Est Travel Reimb Non-Fed Members nextFY*$7,824.00
Travel Reimb. For Federal Members*$0.00Est Travel Reimb For Fed Members*$0.00
Travel Reimb. For Federal Staff*$0.00Est. Travel Reimb to Fed Staff Next FY*$0.00
Travel Reimb. For Consultants*$0.00Est Travel Reimb to Consultants Next FY*$0.00
Other Costs$55,673.00Est. Other Costs Next FY*$56,786.00
Total Costs$130,193.00Est. Total Next FY*$130,751.00
Date Cost Last Modified10/14/2022 11:05 AMEst. Fed Staff Support Next FY*0.40
Federal Staff Support (FTE)*0.40Est Cost RemarksMeetings were held virtually in FY22 due to the ongoing COVID-19 pandemic. Projected costs for FY23 were increased in the event that in-person/hybrid meetings resume.
Cost RemarksThere was a dramatic decrease in federal staff support costs between FY21 and FY22 because in FY21 there were five BSC meetings. NTPBSC developed a new approach for BSC engagement in remote environment over time and as a result in FY22 there were two BSC meetings.  
Hide Section - Interest Areas

Interest Areas

Health and Health Research


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No Documents Found



Data from Previous Years

ActionCommittee System IDCommittee NameFiscal Year
 COM-040277National Toxicology Program Board of Scientific Counselors2021
 COM-038552National Toxicology Program Board of Scientific Counselors2020
 COM-036424National Toxicology Program Board of Scientific Counselors2019
 COM-034630National Toxicology Program Board of Scientific Counselors2018
 COM-001866National Toxicology Program Board of Scientific Counselors2017
 COM-002580National Toxicology Program Board of Scientific Counselors2016
 COM-003806National Toxicology Program Board of Scientific Counselors2015
 COM-004369National Toxicology Program Board of Scientific Counselors2014
 COM-006183National Toxicology Program Board of Scientific Counselors2013
 COM-006837National Toxicology Program Board of Scientific Counselors2012
 COM-008295National Toxicology Program Board of Scientific Counselors2011
 COM-009110National Toxicology Program Board of Scientific Counselors2010
 COM-010058National Toxicology Program Board of Scientific Counselors2009
 COM-010958National Toxicology Program Board of Scientific Counselors2008
 COM-012157National Toxicology Program Board of Scientific Counselors2007
 COM-012499National Toxicology Program Board of Scientific Counselors2006
 COM-013977National Toxicology Program Board of Scientific Counselors2005
 COM-014513National Toxicology Program Board of Scientific Counselors2004
 COM-015993National Toxicology Program Board of Scientific Counselors2003
 COM-016402National Toxicology Program Board of Scientific Counselors2002
 COM-017819National Toxicology Program Board of Scientific Counselors2001
 COM-018588National Toxicology Program Board of Scientific Counselors2000
 COM-019855National Toxicology Program Board of Scientific Counselors1999
 COM-020613National Toxicology Program Board of Scientific Counselors1998
 COM-021463National Toxicology Program Board of Scientific Counselors1997